Pharmacological Evaluation and Prediction of Pharmaceutical Potential of Lasiococca comberi Haines: A Threatened Medicinal Tree
Keywords:
Antimicrobial activities, Artemia salina, pharmacological values, phytochemical screening, Thin Layer Chromatography, threatenedAbstract
Antimicrobial resistance (AMR) is a critical health issue that requires the exploration of unexplored plants for the identification of new therapeutic agents. This study examined the leaves of Lasiococca comberi, a threatened Indian tree species, focusing on its phytochemical content, toxicity, antibacterial activity, and antioxidant potential. Aqueous extract of the leaves showed the highest presence of secondary metabolites, while the methanol and ethanol extracts demonstrated the lowest minimum inhibitory concentration (MIC). Thin-layer chromatography (TLC) analysis of the ethanol extract revealed seven distinct spots and confirmed its antioxidant activity. The quantification of secondary metabolites highlights the potential of L. comberi leaves as a valuable source of bioactive compounds to combat AMR. These findings suggest that L. comberi leaves could be a promising source of new antimicrobial agents, warranting further pharmacological investigation.
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Copyright (c) 2025 Jeline Rani J, Kadambini Das, Jaydeep Kumar Sahu, Shikha Thakur, Sandhya Sharma, Sanjeet Kumar
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